Subacute Necrotizing Encephalomyelopathy and MT-CO1
Protein Interactions
It is important to consider the protein interactions of Cytochrome c Oxidase subunit 1. Much like the gene ontology databases, this will help determine the the function of the protein of interest. Osprey was unable to yield results.
STRING
STRING of Cytochrome c Oxidase subunit 1 Interactions
STRING was able find interactions of Cytochrome c Oxidase subunit 1 in multiple organisms. however, the focus was placed on Homo sapiens. The proteins are labeled with the gene's that encode them. The interactions are represented as the lines that run in between the bubbles, and the color refers to the type of interaction. It is possible to expand or focus the view, and branch out to other organisms.
It is not surprising that the proteins found in the interactions were those within the Cytochrome c Oxidase complex, or other proteins used in the electron transport chain.
It is not surprising that the proteins found in the interactions were those within the Cytochrome c Oxidase complex, or other proteins used in the electron transport chain.
IntAct
The IntAct online database was unable to create a visual description of the interactions. Only one was found in which was with C-type lectin domain family 4 member G. This protein family is involved of binding proteins to a membrane. Therefore, it is most-likely that the cytochrome c oxidase is bound to the inner mitochondrial membrane through the C-type lectin domain family 4 member G.
